Paediatric Society Of Ghana: The Acellular Pertussis Hexavalent Vaccine

A hexavalent vaccine containing acellular pertussis components provides protection against six diseases: diphtheria, tetanus, pertussis, hepatitis B, polio, and Haemophilus influenzae type b (Hib).
Here’s a more detailed explanation:
- What it is:A hexavalent vaccine is a combination vaccine that protects against multiple diseases in a single injection.
- Components:
- Acellular Pertussis: This component uses purified proteins from the pertussis bacteria (Bordetella pertussis) instead of whole cells, which reduces the risk of side effects.
- Diphtheria, Tetanus, and Polio: These are inactivated bacterial or viral components that stimulate the immune system to produce antibodies against these diseases.
- Hepatitis B: This component contains a protein from the surface of the hepatitis B virus, which triggers the body to produce antibodies against the virus.
- Haemophilus influenzae type b (Hib): This component is a polysaccharide capsule from the Hib bacteria, which triggers the body to produce antibodies against the bacteria.
- Diseases Protected Against:
- Diphtheria: A highly contagious bacterial infection that can cause severe breathing problems and heart failure.
- Tetanus: A bacterial disease that causes muscle spasms and paralysis.
- Pertussis (Whooping Cough): A highly contagious respiratory infection that can be severe, especially in infants.
- Hepatitis B: A viral infection that can cause liver damage and chronic illness.
- Polio: A highly contagious viral infection that can cause paralysis.
- Haemophilus influenzae type b (Hib): A bacterial infection that can cause serious illnesses like meningitis and pneumonia.
- Importance:Vaccination against these diseases is crucial for protecting children from potentially life-threatening illnesses.
- Availability:Hexavalent vaccines are widely available in many countries and are a standard part of childhood immunization schedules.

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